Friday, April 18, 2014

Don't fear the NEIDL

The National Emerging Infectious Diseases Laboratory (NEIDL) is a $200 million dollar public health laboratory in Boston, Mass, operated by Boston University. They preform research on multiple pathogens of significant concern to public health, including Tuberculosis, which is a mounting problem in the face of the HIV and antibiotic resistance epidemics. The only problem with their laboratory is that a whole section of it- the Biohazard Safety Level 4 (BSL 4) lab- has never operated in its designed capacity due to multiple legal hurdles the NEIDL had to clear in order to prove that it was safe. First, they were required to prove that their operation was safe, and their security and biosafety measures were deemed effective by an outside company. After that, the NEIDL won a legal suit, in which a judge deemed that their biosafety measures were adequate for safe operation in south Boston. For a better idea of their security and biosafety measures, you can watch a video tour of the BSL-4 facilities at link [1]. At a glance, however, this should give you some idea of their security- if there's a fire, the fire department doesn't get in without being stopped at the gates and individually ID'd and cross-referenced to their list of Boston city firemen. If the power goes out and the negative pressure system fails, all air from the lab is drawn through multiple custom HEPA filters to remove any particulate. On top of the security and engineering controls, the facility operates under the direct supervision of the Boston Public Health, and the CDC.

Now, having cleared all other hurdles, the NEIDL is coming under fire from Boston city council member Charles Yancey, who wants to pass a city ordinance banning BSL-4 research. After all, who wants that sort of research going on in their back yard? What if there's a release? Of course, this sort of NIMBYism (Not In My Back Yard) fails to account for other sites, such as the CDC campus in downtown Atlanta, that have successfully operated BSL-4 facilities for years without a single problem. In fact, there are six BSL-4 labs in operation across the country right now, with seven more planned or under construction, with no reportable incidents yet. In fact, with about 3,000 Americans dying every year from foodborne illness, you're roughly 3,000 times more likely (more than that, since the number of BSL4 releases in the US is actually zero, not one) to be killed by a pathogen from your local fast food operation than you are to be killed by some exotic disease that somehow managed to slip through the NEIDL's biosafety measures. [3][4]

What's more is that Mr. Yancey is calling for this ban without accepting multiple offers on the NEIDL's part to give him a tour. So, the next question is, could Mr. Yancey actually succeed here? Unfortunately, the answer is yes. In 2002, shortly after the 9/11 attacks and Anthrax bioterrorism incidents, UC Davis attempted to get permission to build a BSL-4 laboratory. This attempt was subsequently rejected by the community, and the attempt was shut down for little more reason than unfounded fear, much like the situation in Boston. [5]

So what do we lose if the NEIDL is shut down? We lose out on another BSL-4 facility that could preform vital, life-saving research on emerging and clinically important pathogens in a safe setting. If we already had two dozen of these labs, it wouldn't be too big of a deal, but the fact is that we've only got six in operation now, so a seventh lab could actually mean a significant increase in clinical progress in treating globally important infections. Tired of big government waste? You're looking at it right here- a multimillion dollar public health lab being threatened because some politicians think these viruses are scary, not for any reason that's evidence based. So, what can you do? You can share this article with your friends (PLEASE share, if you ever share one of my articles, let it be this one), spread the word about what's going on in Boston, and sign this petition. http://petitions.moveon.org/sign/let-the-bsl-4-lab-open

Together, we can save the NEIDL. Together, we can save SCIENCE!



[5]http://daviswiki.org/Biosafety_Level_4_Laboratory
[4]http://www.cdc.gov/foodsafety/cdc-and-food-safety.html
[3]http://www.fas.org/programs/bio/research.html
[2]http://www.bu.edu/today/2014/researchers-cite-experts-findings-of-neidl-safety/
[1]http://www.twiv.tv/threading-the-neidl/

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